Adenovirus vectors for gene therapy

Details Adenovirus vectors for gene therapy Adenovirus vectors for gene therapy

1994-05-31

2000-10-31

Guzo, David

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

4353201, 435455, 435456, 435 914, 536 2372, 536 241, C12N 1563, C12N 1564, C12N 15861, C07H 2104

Patent

active

061400874

ABSTRACT:
The invention comprises a series of adenovirus-based vectors having deletions in the E1 and/or E3 regions, and also insertions of pBR322 sequences, which can be used to deliver nucleic acid inserts into host cells, tissues or organisms that then can express the insert. The invention includes the use of the vectors in introducing genes into cells, in making vaccines and in gene therapy.

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