Adenosine receptor prodrugs

Details Adenosine receptor prodrugs Adenosine receptor prodrugs

1987-01-02

1990-11-06

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 17, 514 18, 514263, 530329, 530331, 530332, 536 26, 536 27, 544273, A61K 3152

Patent

active

049686720

ABSTRACT:
A functionalized congener approach to drugs acting at A.sub.1 and A.sub.2 adenosine receptor types is applicable to prodrug design. The prodrugs affect a more efficient delivery of the drug at the particular site of the body affected and take advantage of selective biochemical cleavages and alteration in distribution characteristics. In particular, kidney functions and lipid functions are stressed in the invention.

REFERENCES:
patent: 4696932 (1987-09-01), Jacobson et al.
Jacobson et al., The Chemical Abstracts, 107: 59455h (1987).

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