Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1990-01-09
1991-01-15
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 24, 536 26, A61K 3170, C07H 19167
Patent
active
049854097
ABSTRACT:
The present invention relates to novel adenosine derivatives having the formula (I): ##STR1## wherein R is a lower alkyl group; R' is hydrogen or a lower alkyl group; X is a cycloalkyl group, an alkyl group having at least one hydroxy group, an alkyl group having at least one phenyl group, a bicycloalkyl group, a naphthylalkyl group, an acenaphthylenylalkyl group or a group of the formula (II) or (III); ##STR2## Z is hydrogen, a hydroxy group or a lower alkoxy group, Q is hydrogen or a hydroxy group, A is --CH.sub.2 --, --O--, --S-- or shows a direct connection; Y is --(CH.sub.2).sub.n -- or shows a direct connection; n is an integer of 1 to 3; and the broken line is a double bond or a single bond.
and pharmaceutically acceptable salt thereof, which are useful as antihypertensive agents.
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Kageyama Ken-ichi
Yamada Toshio
Brown Johnnie R.
Crane L. Eric
Nippon Zoki Pharmaceutical Co. Ltd.
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