Adenosine antagonists in the treatment and diagnosis of A-V node

Details Adenosine antagonists in the treatment and diagnosis of A-V node Adenosine antagonists in the treatment and diagnosis of A-V node

1980-10-14

1982-12-21

Fagelson, Anna P.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

424253, 424265, A61K 4900, A61K 3152, A61K 3146

Patent

active

043649220

ABSTRACT:
A method of relieving atrioventricular conduction block by administering to a human or animal an effective amount of an adenosine antagonist that competitively inhibits adenosine or that reduces the level of adenosine present in myocardial tissue and associated fluids. A method of diagnosing atrioventricular conduction block caused by ischemia of the heart by measuring the time delay between atrial and ventricular excitation before and after the administration of an adenosine antagonist. Specific antagonists disclosed include methylxanthines.

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