Adenosine and guanosine-3'-5'-cyclic methylphosphonate derivativ

Details Adenosine and guanosine-3'-5'-cyclic methylphosphonate derivativ Adenosine and guanosine-3'-5'-cyclic methylphosphonate derivativ

1994-01-13

1996-09-24

Kunz, Gary L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 47, 536 2612, 536 2613, A61K 3170, C07H 19167, C07H 19173

Patent

active

055591027

ABSTRACT:
Cyclic AMP and cyclic GMP derivatives, such as 8-bromoadenosine-3', 5'-cyclic methylphosphonate, are effective in inhibiting phosphodiesterases.

REFERENCES:
patent: 3560478 (1971-02-01), Myers
patent: 4058659 (1977-11-01), Robins et al.
patent: 4401808 (1983-08-01), Yamaji et al.
patent: 4567254 (1986-01-01), Kataoka et al.
patent: 4873227 (1989-10-01), Ikada et al.
Meyer, Jr. et al. J. Med. Chem. vol, 16, pp. 1319-1323 (1973).
Meyer, Jr. et al. Life Sciences 14:1019-1040, 1974.

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