Adenosine A2a receptor antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S257000, C514S217010, C544S115000, C544S251000, C540S594000

Reexamination Certificate

active

06916811

ABSTRACT:
Disclosed herein are compounds having the structural formula Aincluding pharmaceutically acceptable salts or solvates of said compound, wherein X, Y, Q and R are as defined in the specification; pharmaceutical compositions thereof; methods of treating central nervous system diseases by administering the compound of the present invention to a patient in need of such treatment, and processes for preparing the compound of this invention.

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Pier Giovanni Baraldi et al., Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine Derivatives: Potent and Selective A2AAdenosine Antagonists, J. Med. Chem., 1996, 39(5), 1164-1171.
Camille G. Wermuth, Molecular Variations Based on Isosteric Replacements, The Practice of Medicinal Chemistry, 1996, XP-002190259, 203-237.

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