Adeno-associated virus vectors

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S320100, C435S455000, C435S456000, C435S457000, C435S069100, C435S183000, C435S325000, C435S349000, C435S350000, C435S351000, C435S366000, C435S363000, C435S368000, C435S370000, C435S371000, C435S372000

Reexamination Certificate

active

06897045

ABSTRACT:
The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors.

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