Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Reexamination Certificate
2006-09-26
2006-09-26
Priebe, Scott D. (Department: 1633)
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
C514S04400A, C435S320100, C435S455000, C435S456000
Reexamination Certificate
active
07112321
ABSTRACT:
Compositions and methods for delivering GDNF to skeletal muscles to result in a therapeutic effect are disclosed. The compositions and methods use adeno-associated virus (AAV)-based gene delivery systems. The methods are useful for treating motoneuron diseases, such as amyotrophic lateral sclerosis (ALS).
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Mizukami Hiroaki
Muramatsu Shin-ichi
Nakano Imaharu
Ozawa Keiya
Wang Lijun
Genzyme Corporation
Priebe Scott D.
Robins & Pasternak LLP
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