Adeno-associated virus (AAV) serotype 8 sequences, vectors...

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

Reexamination Certificate

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C424S093100, C424S093600, C435S320100, C435S235100, C435S069100, C435S069600, C435S325000, C435S455000, C435S456000, C530S350000, C530S324000, C530S325000, C530S326000, C530S327000, C530S328000

Reexamination Certificate

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10423704

ABSTRACT:
Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles. rAAV8-mediated delivery of therapeutic and immunogenic genes, including Factor VIII, is also provided.

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