Adeno-associated viral (AAV) liposomes and methods related there

Details Adeno-associated viral (AAV) liposomes and methods related there Adeno-associated viral (AAV) liposomes and methods related there

1994-09-12

1998-11-10

Campbell, Bruce R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

424 9321, 424450, 435 691, 4351723, 4353201, 435325, 536 241, 935 22, 935 34, 935 56, 935 60, 935 62, 935 70, A01N 6300, A61K 4800, A61K 9127, C12N 500

Patent

active

058344411

ABSTRACT:
A composition for genetic manipulation which comprises a liposome comprised of lipid material, and adeno-associated viral (AAV) material. Typically, the AAV material is plasmid, and comprises a terminal repeat of the AAV genome. Methods are disclosed for introducing genetic material into cells by use of AAV liposomes. Accordingly, genetic material was introduced and integrated into stem cells, T cells, primary tumor cells, or tumor cell lines.

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