Adeno-associated viral (AAV) liposomes and methods related there

Details Adeno-associated viral (AAV) liposomes and methods related there Adeno-associated viral (AAV) liposomes and methods related there

1995-06-02

1999-01-19

Guzo, David

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424 932, 424 936, 4351723, A61K 9127, A61K 48001

Patent

active

058611711

ABSTRACT:
A composition for genetic manipulation which comprises a liposome comprised of lipid material, and adeno-associated viral (AAV) material. Typically, the AAV material is plasmid, and comprises a terminal repeat of the AAV genome. Methods are disclosed for introducing genetic material into cells by use of AAV liposomes. Accordingly, genetic material was introduced and integrated into stem cells, T cells, primary tumor cells, or tumor cell lines.

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