Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2008-04-01
2008-04-01
Whiteman, Brian (Department: 1635)
Chemistry: molecular biology and microbiology
Vector, per se
Reexamination Certificate
active
10632645
ABSTRACT:
One form of a composition has two types of recombinant adeno-associated virus. The first type encodes a portion of Factor VIII operably linked to an expression control element; and the second type encodes a different portion of Factor VIII operably linked to an expression control element. The first and second nucleotide sequences collectively encode a functional Factor VIII protein. Another form of the composition is a recombinant adeno-associated virus containing a nucleotide sequence encoding functional Factor VIII light or heavy chain operably linked to a tissue-specific promoter.
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Colosi Peter C.
Couto Linda B.
Qian Xiaobing
Genzyme Corporation
Whiteman Brian
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