Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-01-02
2007-01-02
Berch, Mark L. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S263210, C514S263220, C514S263370, C544S276000
Reexamination Certificate
active
10474199
ABSTRACT:
This invention relates to an adenine derivative, a tautomer thereof, or a pharmaceutically acceptable salt thereof represented by general formula (I):wherein X represents NR3(wherein R3represents a hydrogen atom or C1-3alkyl) or the like; R1represents substituted or unsubstituted alkyl or the like; R2represents hydroxyl or the like; and Y represents a substituted or unsubstituted aromatic hetero ring or the like. Also, the present invention relates to pharmaceuticals such as an interferon inducer, antiviral agent, anticancer agent, type 2 helper T cell selective immune response inhibitor, antiallergic agent, and immune response modulator comprising the above derivative as an active ingredient.
REFERENCES:
patent: 2705715 (1955-04-01), Baker et al.
patent: 4689338 (1987-08-01), Gerster
patent: 4698348 (1987-10-01), Gerster
patent: 4714701 (1987-12-01), Beauchamp
patent: 4772606 (1988-09-01), Sircar et al.
patent: 6028076 (2000-02-01), Hirota et al.
patent: 6329381 (2001-12-01), Kurimoto et al.
patent: 2003/0149060 (2003-08-01), Cristalli
patent: 2003/0191086 (2003-10-01), Hanus et al.
patent: 2006/0052403 (2006-03-01), Isobe et al.
Patent Abstracts of Japan Abstract of JP 11-193282.
Partial Translation of JP 48-16519.
G. D. Mayer, et al., Science, vol. 169, pp. 1214-1215 1970.
F. R. Nichol, et al., “Stimulation of Murine Interferon by a Substituted Pyrimidine”, Antimicrobial Agents and Chemotherapy, vol. 9, No. 3, pp. 433-439 1976.
D. A. Stringfellow, et al., “Antiviral and Interferon-Inducing Properties of 1,5-Diamino Anthraquinones”, Antimicrobial Agents and Chemotherapy, vol. 15, No. 1, pp. 111-118.
Michael J. Reiter, et al., “Cytokine induction in mice by the immunomodulator imiquimod”, Journal of Leukocyte Biology, vol. 55, pp. 234-240 1994.
Isobe Yoshiaki
Kawakami Hajime
Kurimoto Ayumu
Ogino Tetsuhiro
Ogita Haruhisa
Berch Mark L.
Dainippon Simitomo Pharma Co., Ltd.
LandOfFree
Adenine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Adenine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Adenine derivatives will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3812179