Additives to tampons

Details Additives to tampons Additives to tampons

1995-06-06

1997-10-21

Phelan, D. Gabrielle

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424404, 424411, 424446, 604360, 604904, A61F 1302

Patent

active

056793693

ABSTRACT:
Absorbent products, especially catamenial tampons, for absorbing body fluids, such as menstrual fluid, blood and wound exudates, comprise an amount of a compound effective to inhibit the production of toxic shock syndrome toxin-1 by Staphylococcus aureus bacteria when the products are brought into contact with the bacteria. The compound is selected from the group consisting of monoesters of a polyhydric aliphatic alcohol and a C.sub.8 -C.sub.18 fatty acid; diesters of a polyhydric aliphatic alcohol and a C.sub.8 -C.sub.18 fatty acid; and mixtures thereof. The monoesters and diesters have at least one hydroxyl group associated with their aliphatic alcohol residue.

REFERENCES:
patent: 3052607 (1962-09-01), Hirsh
patent: 3219525 (1965-11-01), Berkow et al.
patent: 3584119 (1971-06-01), Langley
patent: 3970759 (1976-07-01), Frankenfeld et al.
patent: 4022775 (1977-05-01), Kabara
patent: 4067997 (1978-01-01), Kabara
patent: 4113851 (1978-09-01), Leveen et al.
patent: 4347237 (1982-08-01), Evenstad et al.
patent: 4374522 (1983-02-01), Olevsky
patent: 4393871 (1983-07-01), Vorhauer et al.
patent: 4405323 (1983-09-01), Auerbach
patent: 4413986 (1983-11-01), Jacobs
patent: 4431427 (1984-02-01), Lefren et al.
patent: 4485029 (1984-11-01), Kato et al.
patent: 4551148 (1985-11-01), Riley et al.
patent: 4582717 (1986-04-01), von Bittera et al.
patent: 4585792 (1986-04-01), Jacob et al.
patent: 4722936 (1988-02-01), Jacob
patent: 4722937 (1988-02-01), Jacob et al.
patent: 4769021 (1988-09-01), Kass
patent: 4788060 (1988-11-01), Endicott et al.
patent: 4788180 (1988-11-01), Bloch
patent: 4921694 (1990-05-01), Hoppe et al.
patent: 4981686 (1991-01-01), Hardy
patent: 4997851 (1991-03-01), Isaacs et al.
patent: 5000749 (1991-03-01), Le Veen et al.
Material Safety Data Sheet for Leomin HSG-R, 1988.
Altenbern, Protease Inhibitors Suppress Enterotoxin B Formation By Staphylococcus Aureus, FEMS Microbiology Letters 3 (1978) pp. 199-202.
Ansari et al., Sodium Bicarbonate Sodium Bicarbonate Douching for Improvement of the Postcoital Test, Fertility and Sterility, vol. 33, No. 6, (Jun. 1980) pp. 608-612.
Flournoy et al., The Role of Lauricidin as an Antimicrobial Agent, Drugs of Today, vol. 21, No. 8, (1985) pp. 373-377.
Gossel, Feminine Hygiene Products: Why Your Advice is Needed, U.S. Pharmacist, (May 1986), pp. 20-27.
Iandolo, Genetic Analysis of Extravellular Toxins of Staphylococcus Aureus, Annu. Rev. Microbiol. (1989) 43: pp. 375-402.
Iandolo et al., Regulation of Staphylococcal Enterotoxin B.sup.1, Infection and Immunity, vol. 16, No. 2 (May 1977), pp. 610-616.
Ibrahim et al., Inhibition of Growth of Staphylococcus Aureus and Enterotoxin-A Production in Cheddar Cheese Prod. with Induced Starter Failure, J. of Food Protec. vol. 44, No. 3, (Mar. 1981) pp. 189-193;
Kabara, Structure-function Relationships of Surfactants as Antimicrobial Agents, J. Soc. Cosmet. Chem., vol. 29, (Nov. 1978), pp. 733-741.
Notermans et al., Effect of Glyceryl Monolaurate on Toxin Production by Clostridium Botulium in Meat Slurry, J. of Food Safety vol. 3, (1981), pp. 83-88.
Orden et al., Detect. of Staph. Enterotoxin and Toxic Shock Synd. Toxin-1 (TSST-1) by (1991), Immunoblot Comb. with a Semiautomated Electrophoresis System, J. of Immuno. Meth. V. 144, pp. 197-202.
Reiser et al., Prod. of Tosic Shock Synd. Toxin 1 by Staph. aureus Restricted to Endogenous Air in Tampons, J. of C1. Microb., vol. 25, No. 8, (Aug. 1987), pp. 1450-1452.
Robbins et al., Produc. of Toxic Shock Synd. Toxin 1 by Staphy. aureus as Determined by Tampon Disk-Membrane-Agar Method, J. of Clin. Microbio., V. 25, No. 8, (Aug. 1987), pp. 1446-1449.
Schlivert, Staphy. Enterotoxi B and Toxic-Shock Synd. Toxin-1 are Significantly Assoc. with Non-Menstrual TSS, The Lancet, May 17, 1986, vol. 1, pp. 1149-1150, (Abstract).
Schlivert et al., Toxic Shock Synd. Staphylococcus Aureus: Effect of Tempons on Toxic Shock Synd. Toxin 1 Production, Obstetrics & Gynecology, vol. 64, No. 5 (Nov. 1984), pp. 666-671.
Smith et al., Entrotoxin A Synthesis in Staphylococcus aureus: Inhibition by Glycerol and Maltose, J. of Gen. Microbiology, (1986), 132, pp. 3375-3380.
Smith et al., Effect of Glucose Analogs on the Synthesis of Staphylococcal Enterotoxin A, Journal of Food Safety 8, (1987), pp. 139-146.
Strobino et al., Exposure to Contraceptive Creams, jellies and Douches and their Effect on the Zygote, Society for Epidemiologic Research: Abstracts, p. 434.
Tierno et al., In vitro Amplification of Toxic Shock Syndrome Toxin-1 by Intravaginal Devices, Contraception, vol. 31, No. 2 (Feb. 1985), pp. 185-194.
Garbe, et al., Staphy. aureus Isolates from Patients with Nonmenstrual Toxic Shock Synd., JAMA, May 3, 1985, 253 (17) pp. 2538-2542.
Humphreys, et al., Enterotoxin Production by Staphy. aureus Isolates from Cases of Septicaemia and from Healthy Carriers, J. Med. Microbiology, Mar. 1989, 28, (3) pp. 163-172.
crass, et al., Involvement of Staphy. Enterotoxins in Nonmenstrual Toxic Shock Synd., J. Clin. Microbiol., Jun. 1986, 23, (6), pp. 1138-1139.

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