Addition salt of acyl-amino acid and .alpha.-aryl amine and proc

Details Addition salt of acyl-amino acid and .alpha.-aryl amine and proc Addition salt of acyl-amino acid and .alpha.-aryl amine and proc

1995-03-21

1997-05-13

Shippen, Michael L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

560157, 560163, 562430, C07C20900

Patent

active

056294506

ABSTRACT:
To produce optically active .alpha.-arylalkylamine from optically impure .alpha.-arylalkylamine.
Optically impure .alpha.-arylalkylamine is mixed with optically active N-acyl-aspartic acid or glutamic acid in a solvent and the resulting two types of diastereomer salts are optically resolved utilizing difference in solubility.

REFERENCES:
patent: 3028430 (1962-04-01), Gillingham
Patent Abstracts of Japan, vol. 18, No. 385 (C-1227), Jul. 20, 1994, JP-A-06 107604, Apr. 19, 1994.
Organic Synthesis, vol. 49, pp. 93-98, 1969, Ault, "R(+)- and S(-)-.alpha.-Phenylethylamine".

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