Addition copolymers of lactide and glycolide and method of prepa

Details Addition copolymers of lactide and glycolide and method of prepa Addition copolymers of lactide and glycolide and method of prepa

1977-06-24

1979-02-06

Anderson, Harold D.

Surgery

Truss

Pad

3 14, 128 92BB, 260823, 528354, A61L 1700, A61F 124

Patent

active

041379217

ABSTRACT:
Relatively high molecular weight, fiber-forming, crystalline copolymers of lactide and glycolide are prepared in a two-stage polymerization process. In the first stage there is prepared a random copolymer of a major proportion of an optically active lactide with a minor proportion of glycolide or d,l-lactide. In the second stage, a major amount of glycolide and a minor amount of lactide monomers are admixed with the copolymer of the first stage and the polymerization resumed until there is obtained a high molecular weight addition copolymer of lactide and glycolide containing from about 50 to 75 wt percent of units derived from glycolide. The polymer is fiber-forming and useful in the preparation of absorbable surgical sutures.

REFERENCES:
patent: 3297033 (1967-01-01), Schmitt et al.
patent: 3422181 (1969-01-01), Chirgwin
patent: 3442871 (1969-05-01), Schmitt et al.
patent: 3636956 (1972-01-01), Schneider
patent: 3839297 (1974-10-01), Wasserman et al.
patent: 3867190 (1975-02-01), Schmitt et al.

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