Adaptive prediction of changes of physiological/pathological...

Surgery – Diagnostic testing – Cardiovascular

Reexamination Certificate

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C600S481000, C600S508000

Reexamination Certificate

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10678773

ABSTRACT:
A method and system predicts changes of physiological/pathological states in a patient, based on sampling, processing and analyzing a plurality of aggregated noisy biomedical signals. A reference database of raw data streams or features is generated by aggregating one or more raw data streams. The features are derived from the raw data streams and represent physiological/pathological states. Each feature consists of biomedical signals of a plurality of patients, wherein several patients have one or more of the physiological/pathological states. A path, which is an individual dynamics, between physiological/pathological states is obtained according to their order of appearance. Then, a prediction of being in physiological/pathological states, or transitions to physiological/pathological states in the patient, is obtained by comparing the individual dynamics with known dynamics, obtained from prior knowledge.

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