Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-05-27
1999-09-07
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544333, 544405, 544238, 544295, 544296, 544182, 544180, 544179, 544357, 544373, 546186, 546187, 546256, 5462777, 514241, 514242, 514253, 514316, 514323, 514333, 514339, C07D40106, C07D40114, A61K 3144, A61K 31505
Patent
active
059487810
ABSTRACT:
This invention relates to a method of treating cancer by administering a compound of the formula wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, E.sup.1, E.sup.2, p, Het' and Het" are defined as indicated in the specification.
REFERENCES:
patent: 4760083 (1988-07-01), Myers et al.
Graham, "Inhibitors of Protein Farnesylation: A New Approach to Cancer Chemotherapy," Exp. Opin. Ther. Patents, vol. 5, No. 12, pp. 1269-1285, 1995.
Nagasu et al., "Inhibition of Human Tumor Xenograft Growth by Treatment with the Farnesyl Transferase Inhibitor B956," Cancer Research, vol. 55, pp. 5310-5314, 1995.
Lyssikatos Joseph P.
Volkmann Robert A.
Ginsburg Paul H.
Kessinger Ann M.
Pfizer Inc
Richardson Peter C.
Shah Mukund J.
LandOfFree
Adamantyl substituted oxindoles as pharmaceutical agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Adamantyl substituted oxindoles as pharmaceutical agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Adamantyl substituted oxindoles as pharmaceutical agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1804665