Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1985-07-02
1988-06-14
Rizzo, Nicholas S.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
544277, 544265, 536 25, 71 92, C07D47334, A61K 3170, A61K 3152
Patent
active
047512920
ABSTRACT:
The present invention comprises novel adamantyl purine derivatives, in which the purine ring is substituted at the 6-position with a moiety incorporating an adamantane ring system. The purine may also be substituted at the 9-position with a carbohydrate, to give a nucleoside analog, or may be unsubstituted at that position.
The substituent at the 6-position contains an adamantane ring system, either substituted or unsubstituted, in which a linker connects a carbon atom in the adamantane ring system with the 6-carbon of the purine ring. This linker consists of a combination of a heteroatom such as N, O or S, which is directly connected to the purine, and a short (five or less) atom chain, consisting either of carbon or other atoms such as N, O or S, with or without additional pendant moieties, which is connected either to the secondary or tertiary carbon of the adamantane ring system. The adamantane ring system itself may be unsubstituted, or substituted with a wide variety of non-ionic groups.
REFERENCES:
patent: 3150124 (1964-09-01), Svarnas
patent: 3257456 (1966-06-01), Smith
patent: 3532748 (1970-10-01), Smith
patent: 3890299 (1975-06-01), Fox
patent: 3926949 (1975-12-01), Fox
patent: 4714697 (1987-12-01), Trivedi et al.
Letham, Cytokinins in Phytohormones and Related Compounds-A Comprehensive Treatise, vol. I, The Biochemistry of Phytohormones, and Related Compounds, Elsevier/North Holland Medical Press, 1978, Amsterdam.
Rizzo Nicholas S.
The Plant Cell Research Institute, Inc.
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