Adamantyl comprising tripeptides, derivatives and hydrochlorides

Details Adamantyl comprising tripeptides, derivatives and hydrochlorides Adamantyl comprising tripeptides, derivatives and hydrochlorides

1990-02-09

1991-11-19

Doll, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530331, 514934, A61K 3700, A61K 3702, C07K 500

Patent

active

050666428

ABSTRACT:
2-Adamantyl- and 1-adamantyl-D/L-glycyl-L-alanyl-D-isoglutamine and their derivatives of the formulae ##STR1## wherein R stands for a hydrogen atom or a MurNAc group, and hydrochlorides thereof,
a process for the preparation thereof and their use to obtain pharmaceuticals, which are particularly indicated for the treatment of viral diseases and tumors and/or immunomodulations in humans and animals.

REFERENCES:
patent: 3705141 (1972-12-01), Krimmel et al.
patent: 4515715 (1985-05-01), Flegel et al.
CA 111:195410z, Flegel, "Prepn. of N-acetylmuramyl-L-alanyl-D-isoglutamine-N-(1-adamantyl)amide", (1989).

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