Acylation of tetralins

Perfume compositions – Perfume compositions – Ring containing active ingredient

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568319, 568323, 568328, 585459, A61K 746

Patent

active

054300150

ABSTRACT:
A method of acetylating 1,2,3,4,-tetrahydro-1,1,2,4,4,7-hexamethylnapthalene (HMT) to produce 6-acetyl-1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethlnaphthalene (acetyl-HMT), comprises subjecting a mixture of 1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethlnaphthalene and or one or more substituted indanes or substituted acetylindanes to a Friedel-Crafts acetylation reaction in the presence of a saturated hydrocarbon solvent.

REFERENCES:
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patent: 4162256 (1979-07-01), Sprecker et al.
patent: 4178311 (1979-12-01), Specker et al.
patent: 4352748 (1982-10-01), Traas et al.
patent: 4466908 (1984-08-01), Specker et al.
patent: 4551573 (1985-11-01), Cobb
patent: 5087720 (1992-02-01), Frank

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