Acylated insulin analogs

Details Acylated insulin analogs Acylated insulin analogs

1994-11-17

1997-12-02

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 4, 514 12, 514 13, 530303, 530324, 530326, A61K 3828, C07K 1462

Patent

active

056936095

ABSTRACT:
The present invention relates to the field of diabetes. More particularly, the invention relates to a monomeric insulin analog wherein the A chain is the naturally occurring sequence of the human insulin A chain and the B chain is modified at either position B28 and B29 or both. The analog is mono-acylated at the N-terminal of the A chain or B chain or at the lysine. The acylated insulin analogs have an extended duration of action.

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