Acylated guanidines and medicaments containing them

Details Acylated guanidines and medicaments containing them Acylated guanidines and medicaments containing them

1981-03-04

1983-03-15

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

560 27, 560 28, 560 29, 564 47, 564 48, 564 56, 564185, 424322, 424324, A61K 3127, A61K 31165, C07C10378, C07C125063

Patent

active

043767834

ABSTRACT:
The novel acylated guanidines, ureas and substituted ureas correspond to the general formula: ##STR1## in which R.sub.1 repesents a substituted or unsubstituted aromatic ring, R.sub.2 represents an alkyl, aryl, or arylalkyl group, R.sub.4 repesents hydrogen or a variously substituted aryl group, X is oxygen or an imine group: NH and Y represent an alkyl aryl alkyloxy or aryloxy group or a hydrogen atom when X represents oxygen or the group COR.sub.3 with R.sub.3 representing an aromatic group, an aryloxy, aralkyloxy or alkyloxy group when X represents the NH group. They are prepared by heating an appropriate compound under reflux with an oxyaminoalcohol, in a suitable solvent. The products are useful as medicaments for the treatment of arterial hypertension, ischemica diseases of the heart and rhythmic disorders of the latter.

REFERENCES:
patent: 3437691 (1969-04-01), Faith
patent: 3542873 (1970-11-01), Faith
patent: 3873600 (1975-03-01), Brandstrom et al.
patent: 4010189 (1977-03-01), Smith

Affiliated with

Also associated with

Rating

Acylated guanidines and medicaments containing them does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Acylated guanidines and medicaments containing them, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Acylated guanidines and medicaments containing them will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1658517