Acylamino oxo or hydroxy substituted alkylamino thiazines and th

Details Acylamino oxo or hydroxy substituted alkylamino thiazines and th Acylamino oxo or hydroxy substituted alkylamino thiazines and th

1984-03-01

1985-04-23

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

2602444, 2602457, 2602455, 260330, 2602393R, 2602393B, 544 54, 514226, C07D27906, C07D28536, A61K 3155, A61K 3154

Patent

active

045129886

ABSTRACT:
Compounds of the formula ##STR1## and X is an oxo substituted thiazine or thiazepine are disclosed. These compounds possess angiotensin converting enzyme inhibition activity and are thus useful as hypotensive agents.

REFERENCES:
patent: 4329473 (1982-05-01), Almquist et al.
patent: 4460579 (1984-07-01), Karanewsky
patent: 4470973 (1984-09-01), Natarajan et al.
Meyer et al., "Angiotensin Converting Enzyme Inhibitors . . . ", J. Med. Chem., 1982, pp. 996-999.

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