Acyl sulfamides for treatment of obesity, diabetes and lipid...

Details Acyl sulfamides for treatment of obesity, diabetes and lipid... Acyl sulfamides for treatment of obesity, diabetes and lipid...

2005-02-08

2005-02-08

O'Sullivan, Peter G. (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S487000, C514S488000, C514S489000, C514S534000, C514S546000, C514S595000, C514S598000, C514S600000, C546S227000, C560S032000, C560S107000, C560S163000, C560S251000, C564S048000, C564S047000, C564S079000

Reexamination Certificate

active

06852738

ABSTRACT:
A class of acyl sulfamides comprises compounds that are potent ligands for PPAR gamma and generally have antagonist or partial agonist activity. The compounds may be useful in the treatment, control or prevention of obesity, non-insulin dependent diabetes mellitus (NIDDM), hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, atherosclerosis, vascular restenosis, inflammation, and other PPAR gamma mediated diseases, disorders and conditions.

REFERENCES:
patent: 5336690 (1994-08-01), Picard et al.
patent: 6653347 (2003-11-01), Palovich et al.
patent: WO 9315047 (1993-08-01), None
patent: WO 9727852 (1997-08-01), None
patent: WO 0023457 (2000-04-01), None

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