Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-09-20
1993-10-19
Friedman, S. J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3144
Patent
active
052545709
ABSTRACT:
The present invention relates to a pharmaceutical composition comprising: (a) a compound of the formula ##STR1## wherein R.sup.1 and R.sup.2 are as defined below; and (b) isosorbide 5-mononitrate or isosorbide 2-mononitrate or glycerol trinitrate or glycerol 1-mononitrate or glycerol 2-mononitrate: and, optionally (c) a pharmaceutically acceptable carrier. The composition is useful in the prevention and treatment of cardiovascular diseases, and is especially useful in the prevention and treatment of angina pectoris and myocardial infarction.
REFERENCES:
Chemical Abstracts, vol. 102, 1985, 149715u.
Chemical Abstracts, vol. 107, 1987, 102646k.
Chemical Abstracts, vol. 107, 1987, 121085t.
Leitold Matyas
Stoss Peter
Butterfield Garth
Friedman S. J.
Ginsburg Paul H.
Pfizer Inc.
Richardson Peter C.
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