Acyl coenzyme A : cholesterol acyltransferase (ACAT)

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 15, 435193, 4352523, 43525411, 435325, 435356, 536 232, C12Q 168, C12N 910, C12N 120, C07H 2104

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059687495

ABSTRACT:
This invention pertains to purified, biologically active acyl coenzyme A: cholesterol acyltransferase (ACAT) and to nucleic acid (DNA or RNA) encoding acyl coenzyme A: cholesterol acyltransferase. The nucleic acid, or a fragment thereof, may be ligated with an expression vector and transfected into cells to express acyl coenzyme A: cholesterol acyltransferase activity in intact cells and in cell-free extracts.

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