Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-10-07
1997-01-28
Fan, Jane
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5462831, A61K 3144, C07D40500
Patent
active
055978355
ABSTRACT:
A novel ACAT inhibitor of formula (I) useful for the treatment of hyperlipidemia produced from Aspergillus fumigatus FM-F-37; derivatives of said ACAT inhibitor, which are separated from the culture of A. fumigatus FM-F-37 or prepared by a chemical process, also possess ACAT inhibition property. ##STR1##
REFERENCES:
CA 121:103731 Jeong et al. 1994.
S. Omura et al., J. Antibiotics, 46, 1168-1169 (1993).
K. Kuroda et al., J. Antibiotics, 46, 1196-1202 (1993).
H. Tomoda et al., J. Antibiotics, 45, 1202-1206 (1992).
H. Tomoda et al., J. Antibiotics, 45, 1207-1214 (1992).
S. Naganuma et al., J. Antibiotics, 45, 1216-1221 (1992).
H. Tomoda et al., J. Antibiotics, 44, 136-143 (1991).
Bok Song H.
Jeong Tae S.
Kim Sung U.
Kim Young K.
Kwon Byoung M.
Fan Jane
Korea Institute of Science and Technology
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