Acyl amino pyridines

Details Acyl amino pyridines Acyl amino pyridines

1983-01-28

1984-08-21

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 77, 546 79, 546 80, 546 81, 546 93, 546270, 546274, C07D49504, C07D47104, C07D21375, A61K 3144

Patent

active

044670915

ABSTRACT:
Novel N-(4-pyridyl)acetamide derivatives having the formula ##STR1## [where R.sup.1 and R.sup.2 are aryl or heteroarly (optionally linked together by a lower alkylene bridge) or one of R.sup.1 and R.sup.2 is aryl or heteroaryl and the other of R.sup.1 and R.sup.2 is lower alkyl or ar(lower)alkyl, R.sup.3 and R.sup.4 are each hydrogen or lower alkyl] and their nontoxic acid addition salts are described. They are chemical intermediates for the preparation of 4-pyridinamine derivatives having the formula ##STR2## which show CNS activity and may be used as antidepressant drugs.

REFERENCES:
Mndzhoyan, et al., "Amdes of the Pyridine and Thiazole Series", Chemical Abstracts 52:4641a.

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