Acyclovir-peptide analogs

Details Acyclovir-peptide analogs Acyclovir-peptide analogs

2008-08-19

2010-11-02

Audet, Maury (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C424S001690, C514S002600

Reexamination Certificate

active

07825086

ABSTRACT:
Dipeptide and tripeptide ester derivatives of acyclovir and its analogs are disclosed which are useful to treat herpes virus infections. Also disclosed is a method for preparing a therapeutic agent for targeted delivery to ocular tissue comprising linking the therapeutic agent to one or more groups of the formula —X—Y-Z(n)-R; wherein each X, Y and Z is independently Met, Val, Thr, Tyr, Trp, Ser, Ala or Gly; each R is independently H or an amino-protecting group; and each n is independently 0 or 1.

REFERENCES:
patent: 7553812 (2009-06-01), Mitra
patent: 2009/0149482 (2009-06-01), Mitra et al.

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