Acyclic tricarboxylic acid compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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560 60, C07L 5948

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active

052547272

ABSTRACT:
Two acyclic tricarboxylic acid compounds have been isolated from the fermentation of Sporormiella intermedia. The compounds and their derivatives may be used as antifungal agents, cholesterol lowering agents and as anticancer agents.

REFERENCES:
patent: 5132320 (1992-07-01), Bergstrom et al.
S. Brandange et al, "Absolute Configuration and of Alkylcitric Acids" Acta Chem Scand., B31 (1977) 307-312.
S. Brandange et al, "Absolute Configuration and Enantioselective Syntheses of Spiculisporic Acid" Acta Chem. Scand. B 38 (1984) 837-844.
J. P. Lellouche et al "Syntheses of (2R, 3S); (2S, 3R) agaric acid-4-.sup.14 c, and (2R, 3R); (2S, 3S) agaric acid 4,4,5,5,-t4" Chem Abstr. 101:130185d (1984).
K. Inoue, "Hair preparations Containing 3 Hydroxy-4-dicarboxypentadecanoic Acid" Chem Abstr. 88:158285y (1978).
H. Thomas et al, "Zur Kenntniss der Agaricinsaure", Liebigs Ann. Chem., 1907, 357, 145-170.

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