Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1992-10-19
1993-10-19
Killos, Paul J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
560 60, C07L 5948
Patent
active
052547272
ABSTRACT:
Two acyclic tricarboxylic acid compounds have been isolated from the fermentation of Sporormiella intermedia. The compounds and their derivatives may be used as antifungal agents, cholesterol lowering agents and as anticancer agents.
REFERENCES:
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S. Brandange et al, "Absolute Configuration and Enantioselective Syntheses of Spiculisporic Acid" Acta Chem. Scand. B 38 (1984) 837-844.
J. P. Lellouche et al "Syntheses of (2R, 3S); (2S, 3R) agaric acid-4-.sup.14 c, and (2R, 3R); (2S, 3S) agaric acid 4,4,5,5,-t4" Chem Abstr. 101:130185d (1984).
K. Inoue, "Hair preparations Containing 3 Hydroxy-4-dicarboxypentadecanoic Acid" Chem Abstr. 88:158285y (1978).
H. Thomas et al, "Zur Kenntniss der Agaricinsaure", Liebigs Ann. Chem., 1907, 357, 145-170.
Dufresne Claude
Ferrell Leslie A.
Jones E. Tracy T.
Caruso Charles M.
Killos Paul J.
Merck & Co. , Inc.
Winokur Melvin
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