Acyclic pyrrolo [2,3-d]pyrimidine analogs as antiviral agents

Details Acyclic pyrrolo [2,3-d]pyrimidine analogs as antiviral agents Acyclic pyrrolo [2,3-d]pyrimidine analogs as antiviral agents

1989-06-21

1990-11-06

Shen, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544280, 544232, A61K 31505, C07D48706

Patent

active

049686860

ABSTRACT:
This invention relates to the use of acyclic substituted pyrrolo[2,3-d]pyrimidine nucleoside analogs in the treatment of viral infections. Such substituted compounds retain antiviral properties present in their parent compounds, yet exhibit significantly decreased levels of cytotoxicity, thereby having therapeutic potential as antiviral agents.

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This invention was made with Government support under contracts numbered NO1AI42554 and NO1A172641 awarded by the National Institute of Allergy and Infectious Diseases. The Government has certain rights in this invention.

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