Acyclic oximyl hepatitis C protease inhibitors

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

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07728148

ABSTRACT:
The present invention discloses compounds of formula I or pharmaceutically acceptable salts, esters, or prodrugs thereof:which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

REFERENCES:
patent: 6323180 (2001-11-01), Linas-Brunet et al.
patent: 6995174 (2006-02-01), Wang et al.
patent: 7132504 (2006-11-01), Scola et al.
patent: 7135462 (2006-11-01), Scola et al.
patent: 7273851 (2007-09-01), Miao et al.
Dorwald F. A. (Side reactions in organic synthesis, 2005, Wiley, VCH, Weinheim, p. IX of Preface).
Herr, J. R.,A Whirlwind Tour of Current Mitsunobu Chemistry. Albany Molecular Research, Inc. Technical report, 1999, vol. 3, No. 19, 1999, pp. 1-36 (particularly pp. 11-12).
U.S. Appl. No. 11/759,080, filed Jun. 6, 2007, Sun et al.

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