Acyclic nucleoside analogs and oligonucleotide sequences contain

Details Acyclic nucleoside analogs and oligonucleotide sequences contain Acyclic nucleoside analogs and oligonucleotide sequences contain

1995-05-26

1996-11-19

Rories, Charles C. P.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 245, 536 243, 536 2431, 536 2432, 536 253, 544276, 544277, C07H 2104, C07H 2102, C07D47334, C07D47318

Patent

active

055764274

ABSTRACT:
Compounds of formula I; ##STR1## wherein R.sup.1 is hydrogen, or a blocking group that is compatible with oligonucleotide synthesis;

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J. Pitha, Adv. in Polymer Sci., (83) pp. 1-16, vol. 50.
K. Schneider et al., J. Am. Chem. Soc., vol. 112 ('90) pp. 453-455.
J. Holt, et al., Mol. Cell. Biol. (Feb. 1993) pp. 963-973.
G. Hoke et al., Nucl. Acids Res., vol. 19 #20 (91) pp. 5743-5748.
C. Stein et al., Science, vol. 261 (Aug. 1993) pp. 1004-1012.
B. Tseng et al., vol. 1 #1 (Mar. 1994) pp. 65-71.

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