Activity-dependent neurotrophic factor

Details Activity-dependent neurotrophic factor Activity-dependent neurotrophic factor

1992-04-22

1998-06-16

Schwadron, Ronald B.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

53038824, 5303889, 5303892, 530412, 530416, 530413, 530417, 530399, 530395, 53038823, 530839, 530300, 435 41, C07K 14475, C07K 1622, C07K 100, C07K 114

Patent

active

057672407

ABSTRACT:
The present invention relates to a purified non-neuronal activity-dependent neurotrophic factor (ADNF) protein that increase the survival of spinal cord neuron cells, cerebral cortical cells and hippocampal neuron cells which has a molecular weight of 16,000 to 18,000 Daltons as determined by sodium dodecyl sulfate polyacrylamide gel electrophoresis, and a basic pI of about 8.1.

REFERENCES:
Brenneman et al., Soc. for Neurosci Abstracts, 17: 754, 1991.
Webster's II New Riverside Dictionary, The Riverside Publishing Co., 1988, p. 1016.
Branch et al., J. Immunol. Methods, 143(2):251-261, 1991 (Abstract thereof).
Wahl et al., J. Immunol. 140(9):3026-32, 1988, (Abstract thereof).
Hall et al., J. Cell Physiol., 141 (1): 154-9, 1989, (Abstract thereof).
Fahey et al., Clin Exp. Immunol. 88: 1-5, 1992.
Fathman et al., Ann. Rev. Immunol. 1, 633-55, 1983.
Brenneman et al. (1987), J. Cell Biol., vol. 104, pp. 1603-1610.
Brenneman et al. (1988), Nature, vol. 335, pp. 632-649.
Waldman (1991), Science vol. 252, pp. 1657-1662.
Goding, Monoclonal Antibodies: Principles and Practice, Chapters 3, pp. 59-93 Academic Press 1986.
Goding, Monoclonal Antibodies: Ratio Principles and practices: Chapter 8, pp. 281-293 Academic Press, 1986.

Affiliated with

Also associated with

Rating

Activity-dependent neurotrophic factor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Activity-dependent neurotrophic factor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Activity-dependent neurotrophic factor will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1726991