Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-11-21
1991-07-16
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514474, A61K 31335, A61K 3134
Patent
active
050326104
ABSTRACT:
The use of L-ascorbic acid, or a pharmaceutically acceptable salt thereof, in combination with 5,6-O-benzylidene-L-ascorbic acid, or 5,6-O-benzylidene-L-ascorbic acid deuterated at least at the 1-position of the aldehyde group of the benzylidene moiety, or a pharmaceutically acceptable salt of such acids, results in a synergistically enhanced cytotoxicity on human carcinoma cells.
REFERENCES:
Cameron et al., Cancer Research 39, 663-681, Mar. 1979.
Borretzen Bernt
Dornish John M.
Larsen Rolf O.
Oftebro Reidar
Pettersen Erick O.
Goldberg Jerome D.
Norsk Hydro AS
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