Activin receptor-like kinase-1 proteins having...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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Details

C424S185100, C424S198100, C435S069100, C435S320100, C435S325000, C435S471000, C536S023500

Reexamination Certificate

active

07932351

ABSTRACT:
A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-beta-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.

REFERENCES:
patent: 6316217 (2001-11-01), Miyazono et al.

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