Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1994-05-17
1996-12-31
Schain, Howard E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 12, 514 17, 514 21, C07K 508, C07K 510, C07K 506
Patent
active
055894615
ABSTRACT:
A method of inhibiting the proliferation rate of hepatocytes in a subject by administering to the subject the free tripeptide of the composition SDK (serine-aspartic acid-lysine) or the salt thereof.
REFERENCES:
patent: 5112811 (1992-05-01), Lenfant et al.
Cecil Textbook of Medicine 19th edition pp. 775-778, 786-796, 801-804 (1992).
J. Med. Chem. 1990, 33, 2122-2127, Synthesis and Activity of NAcSerAspLysPro Analogues on Cellular Interactions between T-Cell . . . Formation.
Cell Tissue Kinet (1990), 99-103, In vivo effect of the tetrapeptide, N-Acetyl-Ser-Asp-Lys-Pro, on the G.sub.1 -S transition of rate hepatocytes .
Schain Howard E.
Touzeau Patricia L.
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