Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1991-08-13
2000-06-20
Kishore, Gollamudi S.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
424401, 424 43, 424 44, 424 45, 514 78, 514169, 514458, 514725, 514937, A61K 9127
Patent
active
060775297
ABSTRACT:
Active ingredient system for the lipid exchange with target structures; methods for their manufacture and their use; and products containing active ingredient systems of this type are disclosed. The active ingredient system for the transfer of lipophilic and/or amphiphilic components to target structures or from such back to the active ingredient system, as well as to their exchange with the target structures, is formed from at least one lipid component with at least one transfer protein. In the method for the manufacture of the active ingredient system, lipid and protein components are combined into systems in different configurations depending on the purpose of its use and its place of use, whereby the specificity results from the lipid used and the transfer protein employed, as well as the direction of the lipid transfer. Active ingredient systems of this type are used in technology, such as the material technology, in medicine, pharmaceuticals and in the area of cosmetology. The active ingredient system is present in products such as sprays, gels, creams or salves.
REFERENCES:
patent: 4812314 (1989-03-01), Barenholz et al.
patent: 5128318 (1992-07-01), Levine et al.
Brown, Chemistry and Phy. of Lipids 38, 1985, p. 79.
Williams BBA 875 (1986) p. 183.
Brown et al Chemistry & Phys. of Lipids 38, (1985) p. 79.
German Search Report, citing reference: Chemistry and Physics of Lipids, 38, 1985, Elsevier Scientific Publishers Ireland Ltd., (S. (page) 79); along with additional pages listed below:
1. Phosphatidylinositol Transfer Proteins: Structure, Catalytic Activity, and Physiological Function, p. 3.
2. Phospholipid Transfer Proteins From Lung, Properties and Possible Physiological Functions, p. 17.
3. The Lipid Binding Site of the Phosphatidylcholine Transfer Protein from Bovine Liver, p. 29.
4. Phospholipid Transfer Proteins in Microorganisms, p. 41; and.
5. The Non-Specific Lipid Transfer Protein (Sterol Carrier Protein 2) from Rat and Bovine Liver, p. 195.
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