Active ingredient dosage device

Details Active ingredient dosage device Active ingredient dosage device

1996-04-05

1999-07-13

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Biocides; animal or insect repellents or attractants

424409, A01N 2508

Patent

active

059223375

ABSTRACT:
A method of making a dosage device is provided including the steps: admixing at least one active ingredient which is a pesticide in solid form at 25.degree. C., is sparingly soluble in water, and has an average particle size of less than 5 microns, with a disintegrating agent, to provide a compressible mix; and compressing the compressible mix into a unitary dosage device capable of disintegrating in water to form a suspension of the active ingredient of a particle size less than about 5 microns in the water.

REFERENCES:
patent: 3639617 (1972-02-01), King
patent: 3657446 (1972-04-01), Blackmore
patent: 4606909 (1986-08-01), Bechgaard et al.
patent: 4677003 (1987-06-01), Redlich et al.
patent: 4943449 (1990-07-01), Aishima et al.
patent: 5516529 (1996-05-01), Zellweger
Chiou W.L. et al., J. Pharm. Sci. 60(a) 1281-1302 (1971), entitled "Pharmaceutical Applications of Solid Dispersion Systems".
J.W. Conine et. al., "Preparation of Solid Pharmaceutical Spheres" Apr. 1970, D+CI, pp. 38-41.
Alfonso R. Gennaro, "Remingtons Pharmaceutical Sciences". 1985, pp. 1615-1623.

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