Active immunization using a siderophore receptor protein

Details Active immunization using a siderophore receptor protein Active immunization using a siderophore receptor protein

1995-02-08

1998-11-03

Sidberry, Hazel F.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

4241841, 4242031, 4242821, 424 933, 424826, 424823, 424824, 4242411, A61K 39102, A61K 3902, A61K 39116, A61K 39108

Patent

active

058304797

ABSTRACT:
The invention provides a vaccine for immunizing poultry and other animals against infection by a gram-negative bacteria, and a method of immunizing an animal using the vaccine. The vaccine may contain purified siderophore receptor proteins derived from a single strain or species of gram-negative bacteria or other organism, which are cross-reactive with siderophores produced by two or more strains, species or genera of gram-negative bacteria. The invention further provides a process for isolating and purifying the siderophore receptor proteins, and for preparing a vaccine containing the proteins. Also provided is a method for diagnosing gram-negative sepsis.

REFERENCES:
patent: 4452775 (1984-06-01), Kent
patent: 4626416 (1986-12-01), DeVoe et al.
patent: 4663161 (1987-05-01), Mannino et al.
patent: 4681761 (1987-07-01), Mietzner et al.
patent: 4748018 (1988-05-01), Stolle et al.
patent: 4871488 (1989-10-01), Mannino et al.
patent: 5141743 (1992-08-01), Schryvers
patent: 5292869 (1994-03-01), Schryvers
patent: 5587166 (1996-12-01), Donachie
Bolin et al, Infection & Immunity 55:1239-1242, 1987.
Klebba et al, Journal of Bacteriology 149:880-888, 1982.
Neilands Ann Rev Microbiol 36:285-309, 1982.
Erdel et al. Infection & Immunity 62:1236-1240, 1994.
Griffiths et al Infection & Immunity 47: 808-813, 1985.
Griffiths et al FEMS Microbiology Letters 16:95-99, 1983.
Ikeda et al Infection & Immunity 56:2499-2502, 1988.
Chant et al. Journal of General Microbiology 131:1503-1509, 1985.
Gilmour et al Vaccine 9:137-140, 1991.
Choi-Kim et al Vet. Microbiol 28:75-92, 1991.
Glisson et al Avian Disease 37:1074-1079, 1993.
Banerjee-Bhatnagar et al., "Expression of Neisseria meningitidis Iron-Regulated Outer Membrane Proteins, Including a 70-Kilodalton Transferrin Receptor, and Their Potential for Use as Vaccines", Infect. Immunity, 58, 2875-2881 (1990).
Boothby et al., "Characterization of Antigens from Mycoplasmas of Animal Origin", Am. J. Vet. Res., 44, 433-439 (1983).
Brogden et al., "Lysates of Turkey-grown Pasteurella multocida: Effects of Solubilizing Agents on the Immunologic Properties of Membrane Vesicles", Am. J. Vet. Res., 44, 428-432 (1983).
Crosa, "The Relationship of Plasmid-Mediated Iron Transport and Bacterial Virulence", Ann. Rev. Microbiol., 38, 69-89 (1984).
El-Shobaki et al., "Mucosal Transferrin and Ferritin Factors in the Regulation of Iron Absorption", Res. Exp. Med., 171, 243-253 (1977).
Filip et al., "Solubilization of the Cytoplasmic Membrane of Escherichia coli by the Ionic Detergent Sodium-Lauryl Sarcosinate", J. Bacteriology, 115, 717-722 (1973).
Finkelstein et al., "Role of Iron in Microbe-Host Interactions", Rev. Infect. Diseases, 5, S759-S777 (1983).
Furugouri, "Iron Binding Substances in the Intestinal Mucosa of Neonatal Piglets", J. Nutr., 107, 487-494 (1977).
Gilleland, Jr. et al., "Perspectives on the Potential for Successful Development of Outer Membrane Protein Vaccines", Eur. J. Clin. Microbiol., 6, 231-233 (1987).
Glisson et al., "In Vivo Antigen Expression by Pasteurella multocida", Avian Diseases, 35, 392-396 (1991).
Goding, Monoclonal Antibodies: Principles and Practice, Academic Press, 162-165 (1986).
Harlow et al., Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory, 689 (1988).
Lu et al., "A Monoclonal Antibody Against a Pasteurella multocida Outer Membrane Protein Protects Rabbits and Mice Against Pasteurellosis", Infect. Immun., 59, 172-180 (1991).
Lu et al., "The Outer Membrane of Pasteurella multocida 3:A Protects Rabbits Against Homologous Challenge", Infect. Immun., 59, 4517-4523 (1991).
Mazurier et al., "Visualization of Lactotransferrin Brush-Border Receptors by Ligand-Blotting", Biochem. Biophys. Acta, 821, 453-460 (1985).
Neilands, "Microbial Iron Compounds", Ann. Rev. Biochem., 50, 715-731 (1981).
Ogawa et al., "Immunochemical and Biological Characterization of Outer Membrane Proteins of Porphyromonas endodontalis", Infect. Immun., 60, 4528-4533 (1992).
Ogunnariwo et al., "Evidence for Non-Siderophore-Mediated Acquisition of Transferrin-Bound Iron by Pasteurella multocida", Microbial Pathogenesis, 11, 47-56 (1991).
Ogunnariwo et al., "Correlation Between the Ability of Haemophilus paragallinarum to Acquire Ovotransferrin-Bound Iron and the Expression of Ovotransferrin-Specific Receptors", Avian Diseases, 36, 655-663 (1992).
Rimler, "Cross-Protection Factor(s) of Pasteurella multocida: Passive Immunization of Turkeys Against Fowl Cholera Caused by Different Serotypes", Avian Diseases, 31, 884-887 (1987).
Rimler et al., "Solubilization of Membrane-Associated Cross-Protection Factor(s) of Pasteurella multocida", Avian Diseases, 35, 258-263 (1989).
Snipes et al., "Plasma- and Iron-regulated Expression of High Molecular Weight Outer Membrane Proteins by Pasteurella multocida", Am. J. Vet. Res., 49, 1336-1338 (1988).
Stuart et al., "Iron-Suppressible Production of Hydroxamate by Escherichia coli Isolates", Infect. Immun., 36, 870-875 (1982).
Truscott et al., "Demonstration of an Outer Membrane Protein with Antiphagocytic Activity from Pasteurella multocida of Avian Origin", Infect. Immunity, 56, 1538-1544 (1988).
Coulton et al., "Protein II Influences Ferrichrome-iron Transport in Escherichia coli K12", J. Gen. Microbiol., 110, 211-220 (1979).
Crichton, Inorganic Biochemistry of Iron Metabolism, Ellis Horwood, 59-63, 234, 239 (1991).
Francis et al., "Immunological Priming with Synthetic Peptides of Foot-and-Mouth Disease Virus", J. Gen. Virol., 66, 2347-2354 (1985).
Helenius et al., "Solubilization of Membranes by Detergents", Biochim. Biophys. Acta, 415, 29-79 (1975).
Hjelmeland, "Solubilization of Native Membrane Proteins", Methods in Enzymology: Guide to Protein Purification, Academic Press, 182, 253-264 (1990).
Hudson et al., Practical Immunology, Oxford, v, 58-59 (3d ed. 1989).
Jousimies et al., "Genetic Analysis of Salmonella minnesota R Mutants with Defects in the Biosynthesis of the Lipopolysaccharide Core", J. of Bacteriology, 119, 753-759 (1974).
Luderitz et al., "Lipopolysaccharides, the O anigens and endotoxins of Gram-negative bacteria: Relationships of chemical structure and biological activity", The Virulence of Escherichia coli, Sussman, ed., The Society for General Microbiology, Academic Press, 73-88 (1985).
Medearis, Jr. et al., "Cell Wall Composition and Virulence in Escherichia Coli", The Journal of Experimental Medicine, 128, 399-414 (1968).
Neugebauer, "Detergents: An Overview", Methods in Enzymology: Guide to Protein Purification, Academic Press, 182, 239-253 (1990).
Osborn et al., "Proteins of the Outer Membrane of Gram-Negative Bacteria", Ann. Rev. Microbiol., 34, 369-422 (1980).
Overbeek et al., "Carumonam Enhances Reactivity of Escherichia coli with Mono- and Polyclonal Antisera to Rough Mutant Escherichia coli J5", J. Clin Microbiol., 25, 1009-1013 (1987).
Sigma Chemical Co., Product Catalogue: Biochemicals, Organic Compounds for Research and Diagnostic Reagents, 1562-1567 (1993).
Danve et al., Vaccine, 11, 1214-1220, 1992.
Hirst et al., Fish & Shellfish Immunology, 4, 29-45, 1994 (Abstract only).
Nilius et al., J. Med. Vet. Mycol., 28, 395-404, 1990 (Abstract only).
Viscar et al., FEMS Microbiology, 79, 225-232, 1991.
Makela et al., J. Bacteriol. 119:760-764 (1974).

Affiliated with

Also associated with

Rating

Active immunization using a siderophore receptor protein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Active immunization using a siderophore receptor protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Active immunization using a siderophore receptor protein will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-686753