Active compounds for use in the treatment of tumors

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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514523, A61K 4900, A61K 31275

Patent

active

050573047

ABSTRACT:
Antitumor compositions and methods in which a cancerostatic agent and an effective amount of (+)-verapamil, (+)-gallopamil, (+)-devapamil and/or (+)-emopamil which reinforce the antitumor action of the cancerostatic agent are administered to a patient either together or in sequence.

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S. Mizuno and A. Ishida, Biochemical and Biophysical Research Communications 107: 1021-1027, 1982.
T. Tsuruo, Cancer Treatment Reports 67: 889-894, 1983.
T. Tsuruo et al., Cancer Res. 44: 5095-5099, 1984.

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