Active compounds

Details Active compounds Active compounds

1987-05-01

1990-07-24

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514409, 514422, 546196, 548407, 548525, 549399, 549404, 549407, A61K 3140, A61K 3135, C07D40504

Patent

active

049435825

ABSTRACT:
Compounds of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein: X, Y and R.sub.1 -R.sub.6 are as defined have blood pressure lowering activity and K+ channel activator activity and are useful in the treatment of hypertension.

REFERENCES:
patent: 4251537 (1981-02-01), Evans et al.
patent: 4363811 (1982-12-01), Evans et al.
patent: 4366163 (1982-12-01), Evans et al.
patent: 4446113 (1984-05-01), Evans et al.
patent: 4481214 (1984-11-01), Evans
patent: 4510152 (1985-04-01), Faruk
patent: 4571406 (1986-02-01), Evans et al.
patent: 4575511 (1986-03-01), Evans et al.
patent: 4610992 (1986-09-01), Evans et al.
patent: 4629734 (1986-12-01), Ashwood
patent: 4687779 (1987-08-01), Evans
patent: 4738963 (1988-04-01), Hamilton et al.
patent: 4772603 (1988-09-01), Evans
patent: 4786639 (1988-11-01), Evans
Evans, et al.; Journal of Medicinal Chemistry, (1983), vol. 26, pp. 1582-1589.
Evans, et al.; Journal of Medicinal Chemistry, (1984), vol. 27, pp. 1127-1131.
Ashwood, et al.; Journal of Medicinal Chemistry, (1986), vol. 29, pp. 2194-2201.

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