Active compound release systems

Details Active compound release systems Active compound release systems

1984-12-14

1986-12-09

Kight, John

Surgery

Controlled release therapeutic device or system

Osmotic or diffusion pumped device or system

128156, 424 83, 604304, 604896, 604897, 548472, 548491, 514420, 514336, 514356, 514406, 514535, 514404, 514375, 514222, 514223, 514448, 514423, 514424, A61F 702

Patent

active

046278524

ABSTRACT:
In a therapeutic system such as a plaster for administration of an active compound through the skin and comprising a covering layer which is essentially impermeable to the active compound, an active coupound reservoir layer and a protective layer which can be pulled off and which is essentially impermeable to the active compound, the improvement wherein the reservoir layer contains about 1-30% of active compound in an elastomer mixture comprising a diene rubber which can optionally be copolymerized with an .alpha.-olefin, mixed with from 0 up to about 70% by weight of a polyisobutylene, polybutadiene oil and/or paraffin oil, and a tackifying resin. Thereby the active compound can be released in regulated relatively large quantity over a prolonged period of time.

REFERENCES:
patent: 3742951 (1973-07-01), Zaffaroni
patent: 4031894 (1977-06-01), Urquhart et al.
patent: 4166125 (1979-08-01), Kigasawa et al.
patent: 4455146 (1984-06-01), Noda et al.

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