Active agent eluting matrices with particulates

Chemistry: analytical and immunological testing – Involving diffusion or migration of antigen or antibody

Reexamination Certificate

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Reexamination Certificate

active

07638344

ABSTRACT:
The present invention is directed to polymeric matrices for the controlled release of a hydrophilic bioactive agent. Generally, the elution control matrix includes a polymeric matrix having a first polymer and a plurality of microparticles that include the hydrophilic bioactive agent. In one embodiment, the matrix includes a polymer comprising hydrophilic and hydrophobic portions. In another embodiment, the microparticles include a crosslinked hydrophilic polymer.

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