Active agent dosage form comprising a matrix and at least two in

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills

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424484, 424486, A61K 924

Patent

active

055342639

ABSTRACT:
The present invention is directed to an active agent dosage form which is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has on its surface two or more insoluble bands. The invention is also directed to the method for making the active agent dosage form.

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patent: 4792448 (1988-12-01), Ramade
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patent: 5256440 (1993-10-01), Appel et al.
patent: 5266332 (1993-11-01), Dong et al.
patent: 5326570 (1994-07-01), Rudnic et al.
Conte, U., et al., Journal of Controlled Release, 26 (1993), pp. 39-47, "Multi-Layered hydrophilic matrices as constant release devices".

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