Activator of peroxisome proliferator-activated receptor δ

Details Activator of peroxisome proliferator-activated receptor δ Activator of peroxisome proliferator-activated receptor δ

2008-07-22

2008-07-22

Powers, Fiona T (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S338000, C514S365000, C514S373000, C514S374000, C514S397000

Reexamination Certificate

active

11544505

ABSTRACT:
A compound represented by the formula (I) or a salt of the compound, and a PPAR-δ activator which contains the compound or salt as the active ingredient:(wherein A represents O or S; B1represents N, etc.; B2represents O, etc.; each of X1and X2represents O, S, a bond, etc.; Y represents C1-8alkylene chain; z represents O or S; R1represents aryl, etc. which can have substituents; R2represents C1-8alkyl, etc.; R3represents C1-8alkyl, C2-8alkenyl, etc.; each of R4and R5represents hydrogen, C1-8alkyl, etc.; and R6represents hydrogen, etc.; provided that each of Z and R3is attached to the benzene ring, and X2is not attached to the benzene ring).

REFERENCES:
patent: 5089514 (1992-02-01), Hulin
patent: 5089541 (1992-02-01), Madgavkar et al.
patent: 5723479 (1998-03-01), Sohda et al.
patent: 6043264 (2000-03-01), Ohtake et al.
patent: 6300364 (2001-10-01), Shimokawa et al.
patent: 6589969 (2003-07-01), Tajima et al.
patent: 6867224 (2005-03-01), Cheng et al.
patent: 7091225 (2006-08-01), Sierra
patent: 7105551 (2006-09-01), Cadilla et al.
patent: 7119104 (2006-10-01), Sakuma et al.
patent: 7157479 (2007-01-01), Gellibert
patent: 7176224 (2007-02-01), Ardecky et al.
patent: 7196107 (2007-03-01), Beswick et al.
patent: 2002/0032330 (2002-03-01), Nomura et al.
patent: 2005/0054674 (2005-03-01), Sakuma et al.
patent: 0 505 322 (1992-09-01), None
patent: 505322 (1992-09-01), None
patent: WO 92/10468 (1992-06-01), None
patent: WO 96/20935 (1996-07-01), None
patent: WO 96/35688 (1996-11-01), None
patent: WO 97/27190 (1997-07-01), None
patent: WO 97/28115 (1997-08-01), None
patent: WO 01/79197 (2001-10-01), None
patent: WO-01/79197 (2001-10-01), None
Machine Translation of JP 2001-354671 (equivalent of WO 01/79197), Sep. 13, 2007.
Leibowitz et al. ,FEBS Letters, 473, 333-336, 2000.
Vosper et al., Journal of Biological Chemistry, 276(47), 44258-44265, 2001.
He, T.-C. et al., 1999,Cell99:335-345.
Isseman, I. et al., 1990,Nature347:645-650.
Kliewer, S. et al., 1992,Nature358:771-774.
Kliewer, S. et al., 1994,Proc Natl Acad Sci USA91:7335-7359.
Lehmann, J. et al., 1997,J Biol Chem272(6):3406-3410.
Mano H., et al., 2000,J Biol Chem175:8126-8132.
He, T.-C., et al.,Cell99:335-345, 1999.
Isseman, I., et al.,Nature347: 645-650, 1990.
Kliewer, S., et al.,Nature358: 771-774, 1992.
Kliewer, S., et al.,Proc Natl Acad Sci USA91: 7335-7359, 1994.
Lehmann, J., et al.,J Biol Chem272(6): 3406-3410, 1997.
Mano, H., et al.,J Biol Chem175: 8126-8132, 2000.

Affiliated with

Also associated with

Rating

Activator of peroxisome proliferator-activated receptor δ does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Activator of peroxisome proliferator-activated receptor δ, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Activator of peroxisome proliferator-activated receptor δ will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3947518