Activated protein C polypeptides and anti-peptide antibodies, di

Details Activated protein C polypeptides and anti-peptide antibodies, di Activated protein C polypeptides and anti-peptide antibodies, di

1991-06-24

1994-01-18

Chan, Christina

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

435692, 435 9021, 43524027, 436536, 424 858, 514 12, 530328, 530326, 530384, 530380, 530381, 530382, 530383, 5303893, 53038826, 53038825, 530324, 530412, A61K 3702, A61K 3900, C12N 900, C07K 1500

Patent

active

052799565

ABSTRACT:
The present invention describes APC polypeptides and anti-peptide antibodies capable of inhibiting activated Protein C anticoagulant activity. The polypeptide and antibody are useful in diagnostic methods and systems for measuring APC in vascular fluid samples. In addition, the polypeptide and anti-peptide antibody are useful in therapeutic methods for inhibiting APC in a human patient.

REFERENCES:
patent: 32011 (1885-10-01), Zimmerman et al.
patent: 4361509 (1982-11-01), Zimmerman et al.
patent: 4834976 (1989-05-01), Rosok et al.
patent: 4918163 (1990-04-01), Young et al.
patent: 5057598 (1991-10-01), Pollack et al.
Waldmann Science 252:1657-1662 1991.
Dahlback, et al., J. Clin. Invest., 66: 583-591 (1980).
Heeb, et al., Thrombosis Res., 52: 33-43 (1988).
Ohlin, et al., Biochem., 29: 644-651 (1990).
Plutzky, et al., Proc. Natl. Acad. Sci. USA, 83: 546-550 (1986).
Solymoss, et al., J. Biol. Chem., 263; 14884-14890 (1988).
Suzuki, et al., J. Biol. Chem., 257: 6556-6564 (1982).
Vehar, et al., Biochem., 19: 401-410 (1980).
Foster, et al Proc Natl Acad Sci 82:4673-4677 1985.

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