Activated polymers and conjugates thereof

Details Activated polymers and conjugates thereof Activated polymers and conjugates thereof

1991-12-12

1992-10-20

Elmore, Carolyn

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

From reactant having at least one -n=c=x group as well as...

528 69, 435181, 530405, 564 51, 564149, 564159, 564163, 564443, 564 50, C08G 1832, C07C27524, C07C27540

Patent

active

051570998

ABSTRACT:
Macromolecular species such as enzymes, proteins, drugs, and solid supports which contain reactive carbonyl, groups or groups which are readily converted to reactive carbonyl groups are modified by reaction with a compound of the formula ##STR1## in which R.sup.1 is H, C.sub.1 -C.sub.20 alkyl, phenyl, (C.sub.1 -C.sub.10 alkyl)-substituted phenyl, or phenyl-substituted C.sub.1 -C.sub.10 alkyl; R.sup.2 is C.sub.2 -C.sub.5 alkylene or (C.sub.1 -C.sub.4 alkoxy)-substituted C.sub.2 -C.sub.5 alkylene; R.sup.3 is ##STR2## R.sup.4 is H or C.sub.1 -C.sub.4 alkyl; n is at least 5; and m is zero or 1.

REFERENCES:
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patent: 2714610 (1955-08-01), Matter
patent: 3789073 (1974-01-01), Narayahan et al.
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patent: 4515981 (1985-05-01), Otani et al.
patent: 4537945 (1985-08-01), Otani et al.
patent: 5041477 (1991-08-01), Hays

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