Activated polyethylene glycol compounds

Details Activated polyethylene glycol compounds Activated polyethylene glycol compounds

2005-11-08

2005-11-08

Powers, Fiona T. (Department: 1626)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

C424S078170

Reexamination Certificate

active

06962954

ABSTRACT:
Novel arylisothiocyanate compounds are described that are useful for activating alcohol-containing macromolecules, for example polyethyleneglycols and cellulose, for covalent linkage to amino-groups of biomolecules, for example polypeptides such as antibodies, enzymes, and proteins.

REFERENCES:
patent: 4220717 (1980-09-01), Kuo
patent: 4356170 (1982-10-01), Jennings et al.
patent: 5349052 (1994-09-01), Delgado et al.
patent: 5585484 (1996-12-01), Acharya et al.
patent: 5750725 (1998-05-01), Acharya et al.
patent: 5880255 (1999-03-01), Delgado et al.
patent: 6017943 (2000-01-01), Acharya et al.
patent: 6312916 (2001-11-01), Kopetzki et al.
patent: 6342244 (2002-01-01), Zalipsky
patent: 0 126 043 (1984-11-01), None
patent: 0126 043 (1984-11-01), None
patent: 0157 899 (1985-10-01), None
patent: 0 157 899 (1986-10-01), None
patent: WO-94/04193 (1994-03-01), None
Jerry E. Squires, “Artificial Blood”, Science, 295:1002, 1004-1005 (Feb. 8, 2002).
J. Milton Harris, ed.,Poly(ethylene Glycol)Chemistry: Biotechnical and Biomedical Applications: Topics in Applied Chemistry, Plenum Press (New York: 1992), pp. 1-379.
J. Milton Harris and Samuel Zalipsky, eds.,Poly(ethylene Glycol)Chemistry and Biological Applications: ACS Symposium Series 680,American Chemical Society Publishing (Washington, D.C.: 1997), p. 1-341.
Shearwater Corporation,Catalog 2001: Polyethylene Glycol and Derivatives for Biomedical Applications,Huntsville, AL 35801, (pp. 1-17).
Susan Budavari, et al., eds.,Merck Index, 11thEd.,Merck & Co., Inc. (Rahway, NJ.: 1989), p. 7275, Compound No. 7268.
Porro et al., “Specific Anitbodies to Diphtheria Toxin and Type 6A Pneumococcal Capsular Polysaccharide Induced By A Model of Semi-Synthetic Glycoconjugate Antigen” (1985)Mol. Immunol.,22:907-919.
Anderson et al., “Vaccines Consisting of Periodate-Cleaved Oligosaccharides from the Capsule of Haemophilus Influenze Type b Coupled to a Protein Carrier: Structural and Temporal Requirements for Priming in the Human Infant,” (1986)J. Immunol.,137:1181-1186.
Witte et al., “Enzymatic Glycoprotein Synthesis: Preparation of Ribonuclease Glycoforms via Enzymatic Glycopeptide Condensation and Glycosylation,” (1997)J. Am. Chem. Soc.,119:2114-2118.
Michael E. Annunziato, et al.,“p-Maleimidophenyl Isocyanate: A Novel Herterobifunctional Linker for Hydroxyl to Thiol Coupling,” Bioconjugate Chem.,4:212-218 (1993).
Aldrich,Aldrich: Catalog Handbook of Fine Chemicals,(1998-1999), p. 83, Product No. 18,627-9.
Belur N. Manjula, et al., “Cys-93-ββ Succinimidophenyl Polyethylene Glycol 2600 Hemoglobin A: (Intramolecular Cross-Bridging of Hemoglobin Outside the Central Cavity,”J. Biol. Chem.,275(8):5527-5534 (2000).
Polymasc Pharmaceuticals, PLC, “Attachment of Polyethylene Glycol (PEG),” taken from www.polymasc.com/PEG/htm (Feb. 8, 2000).
Polymasc Pharmaceuticals, PLC, “Biological Optimisation and Its Importance,” taken from www.polymase.com/PEGii.htm (Feb. 8, 2000).
Kricheldorf, et al. Chemical Abstracts, 95:25583, 1981.
Viswanathan, et al., Indian Journal of Chemistry, 20B, 308-310, 1981.

Affiliated with

Also associated with

Rating

Activated polyethylene glycol compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Activated polyethylene glycol compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Activated polyethylene glycol compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3499914